Seasonal Influenza Vaccine Safety A Summary for Clinicians Seasonal Influenza FluAdverse Events. Pain and other injection site reactions are frequently reported after IIV vaccination in both children and adults. In IIV clinical trials, up to 6. IIV experience pain at the injection site during the first week after vaccination which usually did not interfere with activity. Fever, malaise, myalgia, and other systemic symptoms can occur after vaccination with IIV, most often affecting individuals who have had no previous exposure to the influenza virus antigens in the vaccine e. In adults, the rate of having these symptoms is similar after IIV and after a placebo injection. Vaccine components can on rare occasions cause allergic reactions immediate hypersensitivity. Manifestations of immediate hypersensitivity range from mild urticaria hives and angioedema swelling beneath the skin to anaphylaxis. In some seasons, IIV has been associated with febrile seizures in young children, particularly when given together with 1. PCV1. 3 and diphtheria, tetanus and pertussis DTa. P vaccines. Flu vaccine composition often changes year to year, and CDC and FDA will continue to closely monitor the safety of influenza vaccines each season. GuillainBarr Syndrome GBS following IIV occurs rarely. The cause of GBS, a serious neurological condition that can cause paralysis, is unknown, however, gastrointestinal and upper respiratory infections are known risk factors. IIV, like other injections, can also cause syncope fainting. Contraindications. IIV should not be administered to the following individuals Infants younger than 6 months of age. Seasonal Factors Affecting Business' title='Seasonal Factors Affecting Business' />People who have experienced a severe life threatening allergy to a prior dose of a seasonal influenza vaccine IIV or LAIV. People who have a severe allergy to a component of the IIV vaccine. Health care providers should consult the package inserts for vaccine components. Recommendations for vaccinating patients who are allergic to eggs are available. RIV is approved in individuals aged 1. RIV. If RIV is not available or the recipient is not 1. IIV. Those who have only experienced hives as a reaction to egg may receive IIV, with some additional safety precautions. Good work, but I think there is need to add functional life of components as one of the factors affecting or influencing construction cost estimate. Supply chain strategies generally conform to one of six types. Choose the best one for your organization, and youll manage your business more effectively. Learn more about Titles, Purposes and Scopes at ashrae. Encyclopedia of Business, 2nd ed. Forecasting FaFor. Encyclopedia of Business, 2nd ed. Sales Forecasting ResSec. Individuals with a history of severe life threatening allergy to eating eggs may receive IIV if it is administered by a physician experienced in the recognition and management of severe allergic conditions. Precautions. In general, vaccinations should be deferred when a precaution is present. However, a health care provider may determine that vaccination is indicated in the presence of a precaution because the benefit of protection from the vaccine outweighs the risk for an adverse reaction. The following are precautions for IIV GBS within 6 weeks of a previous dose of an influenza vaccine IIV or LAIVPresence of a moderate or severe acute illness with or without a fever. Individuals who were hospitalized with an acute illness but who are now well enough to be discharged from a hospital can be vaccinated. Seasonal Factors Affecting Business' title='Seasonal Factors Affecting Business' />Taxing Situations. If you dont think tax reform is a makeorbreak ongoing political issue, consider the pain felt when the business meal tax deduction was reduced. Questions to Ask Patients Before Vaccination. Before administering IIV, health care providers should ask the patient about the following Egg allergies Individuals who report egg allergy should be evaluated using the algorithm in Figure 2 of the 2. ACIP influenza guidelines. Reactions or adverse events, including GBS, after prior doses of influenza vaccine. Seasonal Factors Affecting Business' title='Seasonal Factors Affecting Business' />Individuals who have had severe allergies after previous vaccine doses should not be vaccinated. Current health status, including any current acute illness patients with mild illnesses should be able to be safety vaccinated those with moderate to severe acute illnesses with or without fever should be vaccinated at the discretion of the doctor and patient. Safe Vaccine Administration. To reduce the risk of adverse events after vaccination, health care providers should take the following steps IIV should be administered by intramuscular injection, or intradermal injection in the case of intradermal IIV, using appropriate technique 4. KB, 2. 8 pages. Providers vaccinating children and adolescents aged lt 1. IIV formulation is approved for use in children in their patients age group and the proper dose is used. No influenza vaccines are approved for use in infants aged lt 6 months. Providers should consult the ACIP General Recommendations regarding other steps to take that may help prevent adverse events after IIV vaccination. Flucelvax cc. IIV3 is the first U. S. licensed trivalent inactivated influenza vaccine manufactured using cell culture technology. It is indicated for use in individuals 1. IIV3 is administered as an injection and may cause pain, redness, and swelling at the injection site, and may also cause fever, malaise and myalgias which are usually mild and self limited. IIV3 cannot cause influenza. Adverse Events. The most common 1. Contraindicationscc. IIV3 should not be administered to the following Individuals who have had a severe allergic reaction to any component of the vaccine or after previous dose of any influenza vaccine. Precautions. In general, vaccinations should be deferred when a precaution is present. However, a healthcare provider may determine that vaccination is indicated in the presence of a precaution because the benefit of protection from the vaccine outweighs the risk for an adverse reaction. The following are precautions for cc. IIV3 Moderate or severe acute illness with or without fever. History of GBS within 6 weeks of previous influenza vaccination. Questions to Ask Patients Before Vaccination. Before administering cc. IIV3, health care providers should ask the patient about the following Egg allergies Individuals who report egg allergy should be evaluated using the algorithm in Figure 2 of the ACIP General Influenza Recommendations. Reactions or adverse events, including GBS, after prior doses of influenza vaccine individuals who have had severe allergies after previous vaccine doses should not be vaccinated. Current health status, including any current acute illness patients with mild illnesses should be able to be safety vaccinated those with moderate to severe acute illnesses with or without fever should be vaccinated at the discretion of the doctor and patient. Safe Vaccine Administration. To reduce the risk of adverse events after vaccination, health care providers should take the following steps Top of Page. Recombinant Influenza Vaccine RIVFlu. Blok RIV is a recombinant hemagglutinin influenza vaccine available as a trivalent formulation. RIV does not contain any egg protein. RIV is indicated for active immunization against disease caused by influenza virus subtypes A and type B and is approved for use in individuals 1. RIV is administered as an injection and may cause pain, redness, and swelling at the injection site, and may also cause fever, malaise and myalgias which are usually mild and self limited. RIV cannot cause influenza. Read more about how recombinant flu vaccines are made. Vbulletin Download Manager Plugin Firefox. Adverse Events. During clinical trials, the most common injection site reaction was pain 3. Contraindications. RIV should not be administered to the following Individuals who have had a severe allergic reaction e. RIV or to a vaccine component. Precautions. In general, vaccinations should be deferred when a precaution is present.